If you use Kerio Connect as your office mail server then you should be aware that the recent Office 2011 Service Pack 2 (14.2) update released by Microsoft on April 12, 2012 breaks Outlook’s connectivity to your mail server.
If on the other hand you do not use Outlook as your email client (e.g. you use Apple Mail instead) then it is fine to apply this update.
More information on problem can be found at Kerio.com or by following this link.